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Claudio Tavera, a specialist in Integrative and Functional Medicine

Complete loss of GPX4 is incompatible with viability, and pharmacological or genetic GPX4 inhibition is widely exploited to induce ferroptosis in cells and tissues

Glutathione is an important antioxidant and an essential cofactor for antioxidant enzymes, providing protection for functional proteins via the redox buffer for sulfhydryl [8, 9]

Urhoghide, E

doi: 10.3390/ijms19123903 116 ZordokyB

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway