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Kundu, S., Sengupta, S., Chatterjee, S., Mitra, S., & Bhattacharyya, A

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139 GLP-1RA presents two considerations regarding weight-related factors in MASLD

But Drucker, a pioneer in the research of the new drugs who advises companies that make them, said its possible the effect in some people at some dosages could go to an extreme, thereby blunting other reward pathways

Thats because the effect reducing serious cardiovascular events by about 20% is so pronounced

"Patients taking any of these medicines should tell their health professional if they experience new or worsening depression, suicidal thoughts or any unusual changes in mood or behaviour." The TGA stressed there was not enough evidence to conclude the drugs caused those changes