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Although there are still some limitations in the current research, we believe that in the future, systematic nutritional intervention is expected to become the third major treatment alongside physical and drug therapy, benefiting more people

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A deficiency in B12 can lead to fatigue, weakness, numbness, tingling sensations, and memory problems

Other interventions, like non-surgical or surgical skin tightening procedures, can be helpful complements, too

doi:10.1016/j.sleh.2021.05.004

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