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doi: 10.3389/fendo.2024.1503905 Received 29 September 2024 Accepted 09 December 2024 Published 09 January 2025 Volume 15 - 2024 Edited by Weibin Bai, Jinan University, China Reviewed by Zia Ur Rehman, University of Agriculture, Pakistan Kamil Gill, Pomeranian Medical University, Poland Updates Copyright 2025 Saleh, Sallam, Elsuity, Dutta, Sengupta and Nasr

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By age 40, most people with Down syndrome have significant levels of betaamyloid plaques and tau tangles in their brains

GHK-Cu reduced inflammation in the brain by decreasing MCP-1 (monocyte chemoattractant protein-1) staining intensity in the frontal cortex and hippocampus

Glutathione levels take time to build