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Establish concentration-response relationships for specific research objectives and animal models

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In a landmark human trial comparing topical GHK-Cu to vitamin C and retinoic acid (tretinoin), GHK-Cu produced measurable collagen increases in 70% of study volunteers outperforming both comparator treatments (Abdulghani et al., 1998)

Mouse metabolism, mouse fat biology, and mouse dosing all differ from the human versions, and metabolic findings in rodents have a long history of not carrying over cleanly to people

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