Hamilton LE, Suzuki J, Aguila L et al (2019) Sperm-borne glutathione-S-transferase omega 2 accelerates the nuclear decondensation of spermatozoa during fertilization in mice
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This enhanced stability is particularly crucial for ophthalmic applications, where the compound must survive the journey through the cornea, remain active in the aqueous humor, and eventually release carnosine directly into the lens tissue where it exerts its antioxidant effects
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Extrinsic apoptotic pathways are activated by interactions between cell surface exposed death-inducing ligands such as FAS ligands (FASL) and tumor necrosis factor (TNF), and their cognate receptors Fas cell surface death receptor (FAS) and TNF receptor (TNFR) [110, 111]
Belvisi MG, Stretton CD, Barnes PJ