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Beyond 28 days, oxidative degradation and aggregation increase measurably

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Paracellular and transcellular [50] substances produced by microorganisms, including short-chain fatty acids and 4-ethylphenylsulfate, travel through the portal circulation and have an impact on the immune system, metabolism, and nerve cells in the gut's enteric nervous system, as well as on the vagus nerve's afferent fibers [51]

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