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Common adverse effects include gastrointestinal symptoms (nausea, diarrhea, constipation), which typically improve with continued use

Methods The PubMed, Embase, Web of Science, and Scopus databases were searched for randomized controlled trials (RCTs) that explored the efficacy of GLP-1RAs or TZDs in adult patients with NAFLD or NASH

Note: Phase 2 trials also tested a 1 mg starting dose, which showed modest results

Furthermore, considering Gln 13 in exenatide, GLP-1 presumably interact with GLP-1R via a hydrogen bond

Forest plot of GLP-1 receptor agonists versus comparators on the risk of Asthma

Environ Exp Bot 131:6876 Shen C, Yang Y, Liu K, Zhang L, Guo H, Sun T, Wang H (2016) Involvement of endogenous salicylic acid in iron-deficiency responses in Arabidopsis