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Together, these studies suggest that vitamin D and exercise may exert complementary effects on aging biology, but their synergy is likely modulated by individual context, intervention intensity, and underlying risk status, as reviewers have rightly emphasized

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PMID: 25998928

Oxidative stress is involved in endothelial damage resulting from endothelial malfunction, which increases endothelial permeability and inflammatory cell infiltration in the arterial wall [69]

Cigarette smokeinduced oxidative stress