The active forms of endogenous GLP-1 are primarily GLP-1(7-36) amide and, to a lesser extent, GLP-1(7-37)
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Likewise, GLP-1 inhibits VSMC dedifferentiation by regulating mitochondrial dynamics via enhancing adiponectin (APN) expression, which in turn promotes the phosphorylation of AMPK and SIRT1 in VSMC [126, 127]
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The overall heterogeneity for renal outcome was I 2 = 42.3% (95% uncertainty intervals, 0 and 68.0%) (moderate) (Additional file 1: Table S3) with no evidence of publication bias
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