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BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

Clin Transl Sci (2020) 13(1):13746

In this study, we aimed to assess the protective effects of the tetrapeptide Epitalon in an in vitro model of DR using an HG-injured ARPE-19 cell line

We showed that norepinephrine (NE, 50 M) or dopamine (DA, 50 M) exerted potent protective effect against glutamate-induced cytotoxicity, but this effect was not observed when other neurotransmitters such as histamine, -aminobutyric acid, serotonin, glycine and acetylcholine were tested

Collagen is a major component of connective tissues, and its regeneration is crucial for repairing ligaments, tendons, muscles, and even blood vessels

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