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Mode of Action: Linagliptin inhibits DPP - 4, which prolongs the action of GLP - 1 and GIP, leading to improved blood sugar control

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Pharmaceuticals (Basel) 17(12):1655 Picoli CC, Tsibulnikov S, Ho M, Demambro V, Feng T, Eltahir M, Le PT, Chlebek C, Rosen CJ, Ryzhov S, Li Z (2025) Vertical sleeve gastrectomy and semaglutide have distinct effects on skeletal health and heart function in obese male mice