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The extracellular subunit (130 KDa) is sialylated via 2, 6-linkages and binds the IGF-1R ligands (IGF-1, IGF-2), while the intracellular subunit (97 kDa) transmits a downstream signal by autophosphorylating tyrosine residues

A fatty-acid chain binds albumin and stretches the half-life to about six days, so a single weekly subcutaneous administration maintains exposure across trials [6]

doi: 10.1016/j.ymgme.2006.06.009

Bioinformatics 23, 802808

Your provider performs the IV infusion at the Creekside Wellness office, and during the procedure, they place a small catheter into a vein in your arm