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Given how much is circulating online some of it accurate, much of it overstated its worth laying out what the research actually shows, where the gaps are, and how we think about it clinically

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In a large cohort study, nearly all cases of initial thyrotoxicosis evolved late hypothyroidism, with overt thyrotoxicosis occurring a median of 5 weeks after the first ICI dose and overt hypothyroidism developing a median of 14 weeks later (Muir et al

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