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Researchers are also developing peptide analogues, modified versions of natural peptides, to enhance their stability, efficacy, and specificity

The reviews generally conclude that gut microbiome modulation may contribute to the metabolic benefits of GLP-1 receptor agonists, and that probiotics may complement these effects

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42 Yet glycemic endpoints have shown limited improvement

Hartog H, Boezen HM, de Jong MM, Schaapveld M, Wesseling J, van der Graaf WTA