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These findings will facilitate rational structure-based discovery of non-peptide agonists targeting class B GPCRs

The compound did not impact food intake, suggesting it works through metabolic enhancement rather than appetite suppression

Clinical evidence shows that GLP-1 agonists reduce cravings for high-fat and high-sugar foods by modulating reward pathways in the brain

Saudi Arabia Pharmacognosy Res 9(4):401 Alkan H, Cierci H, Ali MM et al (2022) Cytotoxic and genotoxic evaluation of biosynthesized silver nanoparticles using Moringa oleifera on MCF-7 and HUVEC Cell Lines