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A proof-of-concept phase 2 study compared two doses (50 and 150 mg) of this first-in-class drug to placebo in PD patients on dopaminergic treatment with an OFF-time of at least 2 h [152]

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This is a significant phenotype, as a similar reduction in circulating triglycerides was not observed with a liver-specific loss of critical lipogenic enzymes, such as fatty acid synthase (FASN) 81

Hypermagnesemia disturbances in rats, NO-related: pentadecapeptide BPC 157 abrogates, l-NAME and l-arginine worsen

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