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34 Here we review current knowledge of the underlying mechanisms of NADPH homeostasis following its de novo synthesis, relative contribution of related enzymes and pathways in cancer

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4 Brepocitinibs trajectory keeps accelerating This follows: Phase 3 success in dermatomyositis (NDA already submitted) Ongoing Phase 3 trial in noninfectious uveitis Now Phase 3-ready in cutaneous sarcoidosis With Pfizer holding a 25% stake in Priovant Therapeutics, and consensus forecasts projecting ~$2.3B peak sales by 2032, brepocitinib is rapidly evolving into one of the most compelling late-stage autoimmune stories

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doi: 10.1080/17402520600877786

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