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IGF-1 LR3 may raise more concern around blood sugar changes, growth-factor activity, and improper use by beginners

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These findings support the sentiment that paraxanthine is a key metabolite involved in caffeine's stimulant effects, which has been suggested in previous human clinical trials

doi: 10.1016/S0015-0282(00)00518-5 21 ShiMSirardM-A

Intermittent hypoxia: Damages endothelial function Disrupts nocturnal testosterone rhythms Increases sympathetic drive (counterproductive for erections) TRT can worsen untreated OSA by relaxing upper airway musculature

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