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Conversely, [U- 13 C]glucose tracing showed GGCT overexpression enhanced Glc-derived carbon flux into the TCA cycle (increased m + 2 labeling of succinate, fumarate, malate), which was reversed by the E98A mutant (Fig

doi: 10.1210/jc.2013-3589 113 CappolaARDesaiASMediciMCooperLSEganDSopkoGet al