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Their cardiovascular benefits may include better blood sugar regulation, lower blood pressure, reduced triglyceride levels, increased HDL (good) cholesterol, weight loss, and improved clinical outcomes

The detailed search and selection process is visually represented in the PRISMA flow diagram ( Figure 2 )

Without lifestyle changes, many individuals may experience increased appetite, weight regain, and reversal of metabolic improvements

Early clinical trials have generated significant global attention due to its substantial weight loss potential

Hexose-6-Phosphate Dehydrogenase: H6PDH Humans express a second glucose-6-phosphate dehydrogenase activity, referred to as the H form