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Research is ongoing in this context [2]

In all models, daily intraperitoneal injections of TZP (50 nmol/kg for 21 days) resulted in a significant reduction in tumor volume and weight, regardless of diabetic status

Significant distinctions were found between responders and non (or poor) responders with responders achieving greater weight loss of (7.38 1.74 kg vs 2.11 2.17kg, respectively)

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Nausea: 50-66% Diarrhea: 49% Vomiting: 41% Dyspepsia: Elevated risk Discontinuation due to side effects: 15.9-20% The higher side effect rates for Survodutide require context

The Journal of Biological Chemistry 2011