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Although the focus of the study was on systemic lupus erythematosus, the data demonstrate that ferroptosis can occur in neutrophils (170)

Reduced stem cell function leads to the diminished replenishment of the tissue in essentially all adult stem cell compartments

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Taken together, these pharmacokinetic findings indicate that the centrally mediated effects of GLP-1RAs are likely due to limited brain penetration or action at sites adjacent to the BBB, rather than widespread distribution throughout the central nervous system

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