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National and international guidelines consistently position lifestyle modification as the first-line intervention for obesity treatment

Abolishing -arrestin recruitment is necessary for the full metabolic benefits of G protein-biased glucagon-like peptide-1 receptor agonists

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Building on these data, here we assess whether the metabolic effects of such an incretin-conjugated PPAR agonist could further be enhanced by covalent tethering of Tesa to the peptide backbone of the DPP4-protected GLP-1RGIPR co-agonist MAR709 32 (Extended Data Fig

The entire leaf area was selected as ROI for Ca 2+ signal analysis