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Its absorption in the intestine is impaired by calcium, phosphate and iron

These complexes alter the structure, isoelectric point, hydrophobicity, solubility, and susceptibility of the proteins to enzymes (601)

Clinical trials have shown that approximately 44% of Wegovy users reported nausea, compared to 20% of Ozempic users, indicating a higher incidence of gastrointestinal side effects with Wegovy

They help trigger insulin, slow down how fast your stomach empties, and tell your brain youve had enough to eat

This is one reason they need to be taken daily instead of weekly like injections