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A clinically significant interaction exists between tirzepatide and oral contraceptives, requiring backup contraception for 4 weeks after initiation and each dose increase, and patients taking levothyroxine or other time-sensitive medications warrant closer monitoring

Unlike clinics that handle consultations asynchronously, this format could delay treatment by a day or two

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More often than not, patients may need to try lower doses of the medication or an alternative class of GLP-1 agonists, as there is a variation in tolerability profile between them, says Criner