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However, whether circulating or local concentrations of endogenous PACAP [138] are increased in the presence of a DPP4 inhibitor or altered in Dpp4 / mice remains unclear, and it is difficult to ascertain due to the low concentrations of PACAP isoforms in vivo

This research did not receive any specific Grant from funding agencies

Gandasi, N

doi: 10.1038/s41588-017-0011-x 98 AkbariPGilaniASosinaOKosmickiJAKhrimianLFangYYet al

Much of the foundational research also comes from a single research group, which limits the breadth of independent validation

Until more sport-specific research is available, the approach is to use GLP-1 RAs only if medically necessary, and even then, to do so with careful monitoring and support from your medical team