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The Role of Appetite Suppression in Dessert Tolerance Appetite suppression from tirzepatide occurs through dual GLP-1 and GIP receptor activation, which regulates both hunger hormones (ghrelin) and satiety hormones (peptide YY and cholecystokinin)

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Tirzepatide is part of a class of medications known as GLP-1 agonists that have skyrocketed in popularity in recent years