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For targeted therapeutic support during severe symptom flares or intense detoxification protocols, some functional medicine providers may recommend temporarily increasing the dose to 300 mg or 400 mg per day, though this should always be done under medical supervision

In animal models, GLP-1 receptor agonists reduce amyloid plaques, neuroinflammation, and induce changes in microglia that promote a neuroprotective state

Although in some outcomes, GLP-1 RAs and SGLT2is outperformed metformin, considering the low strength of evidence, we would recommend GLP-1 RAs and SGLT2is as second-line drugs for PCOS

RoenRx will manage insurance pre-approvals or offer comparable, lower cost medication if not covered by insurance

Vitamin B12 supports the nervous system and plays a role in the production of mood-regulating neurotransmitters like serotonin

Dietary supplements can not be used as a substitute (replacement) for a varied diet