The retarded leaching of nanoclusters can be attributed to their large size in comparison with molecular dyes and it is a clear advantage for imaging purposes as dye leaching decreases the fluorescence brightness of NPs and increases the background signal resulting in unfavorable imaging inefficiency/artifacts 50
In addition to energy, erythrocytes require reducing power in the form of nicotinamide adenine dinucleotide phosphate (NADP) and NADPH to counteract the oxidative processes in their oxygen-rich environment
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