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In vivo evidence is limited to a murine tooth extraction model treated with lipopolysaccharide injection where TNF-a retarded bone regeneration [196]

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The damage becomes more difficult to reverse

A smaller dose may likely only offer smaller benefits, Zimmermann adds

Healthcare professionals determine whether the product is appropriate for a particular patient based on their clinical evaluation and treatment objectives

Treatment focuses on addressing the underlying cause, controlling symptoms, and preventing complications particularly foot injuries in patients with diabetes who cannot feel pain normally