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Individuals with genetic predispositions to conditions like celiac disease, inflammatory bowel disease, or autoimmune disorders may be more prone to developing increased intestinal permeability

*Correspondence: Ken Takahashi [email protected] This article was submitted to Cardiovascular Metabolism, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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206 GLP-1 has also been shown to reduce blood glucose levels via direct inhibition of glucagon secretion from islet alpha-cells in an insulin-independent manner