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On the basis of microscopic reversibility of enzymatic reactions, the enzyme-catalyzed oxidation of roGFP2(SH) 2 by GSSG or GSSR follows the reverse reaction of mechanism (iii)

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HTLV-1 is the etiological agent of the adult T-cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic progressive disabling disease characterized by demyelination, axonal loss, neuronal degeneration, and gliosis