Among the secondary prevention population ( n =95,247 at baseline), widespread SGLT2i use was projected to prevent 5402 non-fatal MIs, 66,490 HF hospitalisations, 2324 ESKD events and 7000 deaths, but increase the number of non-fatal strokes by 996
BeMediq Why Diet Alone Often Isn't Enough And What GLP-1 Therapy Changes GLP-1 receptor agonists produce up to 15% body weight loss in clinical trials significantly more than diet and exercise alone
A study examining plasma samples from 50 migraine patients and 30 healthy volunteers found that plasma levels of 8-hydroxy-2-deoxyguanosine were significantly higher in migraine patients compared to controls, indicating a connection between migraine and oxidative stress-related DNA damage (Table 1)
This ubiquitous free thiol is not only important for antioxidative protection of the plasma membrane and organelles, but it also plays distinct roles in cell cycle regulation and apoptosis 26,27
Realworld evaluation of the effects of tirzepatide in patients with type 2 diabetes mellitus
Barton-Davis et al