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First, it is able to accumulate specifically in tumor cells, remaining unaffected by MRP while maintaining good cell-membrane permeability

Once the B12-TC2 complex arrives at the cell where it is needed, B12 is released from TC2 in the form of hydroxocobalamin

Therefore, inhibitors of the SCF-KIT signaling pathway can potentially exhibit anti-melanogenesis activity

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Mirzakhani L, Jafarizadeh-Malmiri H, Ahmadi O (2024) Three accelerated methods based on microwave, hydrothermal and conventional heating in the green synthesis of selenium nanoparticles using garlic aqueous extract: Screening and characterization