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Reassuringly, we could demonstrate a ~1.5-fold increase in serine phosphorylation of the WT receptor by acute (5-minute) stimulation with GLP-1

As a result of enzymatic variants, reduced enzyme function may lead to overall reduced methylation

Enhancement of anti-oxidant capacity: curcumin increases the levels of anti-oxidant enzymes such as catalase, superoxide dismutase, and glutathione in the nervous system, skeletal muscles, and circulatory system, mitigating oxidative stress [74]

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However, insulin-sized intracellular products are more limited in number, presumably due to their rapid breakdown by GSH