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doi: 10.1161/JAHA.117.008190 183 KangDWParkMKOhHJLeeDGParkSHChoiKYet al

In a study by Probst et al., dulaglutide was given at a dose of 1.5 mg subcutaneously once weekly for 12 weeks

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It stimulates the production of immunoglobulin (Ig) G and IgM antibodies [99], whereas testosterone has the opposite effect, reducing the production of these immunoglobulins [100]

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Specifically, an initial reduction followed by a substantial increase in beta-endorphin levels was observed, a pattern that suggests DSIPs impact on the opioidergic system, potentially playing a role in stress alleviation or adaptation processes