[DOI] [PMC free article] [PubMed] [Google Scholar] 146.Javonillo DI, Tran KM, Phan J, Hingco E, Kramr EA, da Cunha C
Beyond MTHFR, polymorphisms in genes encoding drug transporters, such as SLC19A1 (rs1051266) and SLCO1B1 (SLCO1B15 and SLCO1B115), have been implicated in MTX transport efficiency and toxicity profiles
In particular, topiramate may control the flow of glutamate and cysteine through System Xc-, which could impact GSH synthesis and improve the ability of GPX4 to change harmful lipid hydroperoxides into safe lipid alcohols
Depletion of carnitine pools is a hallmark of RBC aging in vivo and in vitro, as these pools are essential to fuel the Lands cycle 23
Bulletin of experimental biology and medicine , 161 (1), 175178
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