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Face and prodictive validity

Butyric acid activates the Nrf2 pathway to increase the activity of antioxidant enzymes such as superoxide dismutase (SOD2), catalase (CAT), and glutathione peroxidase (GPx), reduce the oxidative damage caused by ROS, and maintain the integrity of the intestinal barrier 154

Because they are implanted, they must be sterile, and one of the concerns listed in the FDAs warning letter is that BSOs sterilization validation studies are inadequate

Methods The research described in this section complies with all the ethical guidelines of the individual institutions where the studies were conducted, identified at the end of each section listed here

I know it means a lot to finally be able to share this work Very happy to see this excellent work in print