6 The screening model is valuable precisely because it is sensitive, but that sensitivity is also its limitation: many agents that look promising on dermal papilla cells never translate into clinically meaningful regrowth, because a follicle in a dish is insulated from the hormonal, vascular, immune, and mechanical realities of a living scalp
Diets rich in fiber, antioxidants, and anti-inflammatory nutrients, such as the Mediterranean diet, favor beneficial microbial communities, while high-fat, high-sugar diets exacerbate dysbiosis and inflammation (Vinelli et al., 2022
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*Correspondence: Juan Pablo Del Ro, [email protected] This article was submitted to Neuroendocrine Science, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
It significantly reduces both lipolysis and lipogenesis but as the reduction is greater for lipogenesis the net effect is to promote fat mobilization and reduce fat storages (Liang et al., 2015)