[DOI] [PubMed] [Google Scholar] (589).Kroll JO
Ferrannini E, Baldi S, Frascerra S, Astiarraga B, Heise T, Bizzotto R, et al
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There is also the risk of opioid overdose
Studies showing meaningful effects generally used 1,000mg or more per day
But the names used to describe it (lip freckle, sun spot on the lip, age spot, lip melanosis, labial lentigo) are confusing enough that most people cannot tell whether they are dealing with one condition or several