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Lastly, the results of a very recent systematic review and network meta-analysis aimed to compare the effects of oral antidiabetic drugs in endocrine and metabolic profiles in patients with PCOS confirmed that metformin was more beneficial in reducing serum total testosterone, whereas GLP-1RA + metformin reduced FAI more effectively [24]

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I think people should have a conversation with their practitioners or their doctor or provider and do their own individualized risk benefit analysis, he said

2019 Dec;30:72-130

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Aim for roughly 0.6-0.8 grams of protein per pound of your goal body weight per day