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*Correspondence: Keizo Kanasaki, [email protected] Daisuke Koya, [email protected] This article was submitted to Gastrointestinal and Hepatic Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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However, amidst this oxidative onslaught, NRF2 strengthens cellular defenses, particularly by upregulating enzymes such as glutathione S-transferases (GSTs)

"The role of dacarbazine and temozolomide therapy after treatment with immune checkpoint inhibitors in malignant melanoma patients: A case series and meta-analysis"

Many patients who initially struggle with side effects tolerate the medication well after adjustments to their escalation schedule

this compound ameliorated the declines in several behavioral tasks: the Morris water maze, inclined beam-walking, and lateral push tests