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Enpatoran Demonstrates Sustained Benefits in Lupus Over 48 Weeks, suggests study medicaldialogues.in To view or add a comment, sign in In a mouse model of obesity-induced metabolic inflammation that accelerates leukemogenesis dual therapy with an anti-IL-17A antibody and a GLP-1R agonist beinaglutide reduced M2-like TAMs, restoring Ciita-dependent antigen presentation, Tyk2-mediated IFN signaling, reactivated T-cell responses, and reduced leukemic burden