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This results from G3P accumulation upstream and shunting of hexose monophosphates to the oxidative phase of the PPP to generate nicotinamide adenine dinucleotide phosphate (NADPH), which in turn fuels antioxidant systems

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Mechanism, Depth, Biology Here is the molecule, the receptor biology, and the gene-expression data in one place, as primary-sourced as we can make it without turning the section into a review article

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Patients who stop the medication gain back on average two thirds of the weight they had lost