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Do not use concomitantly with NSAIDs and other corticosteroid drugs
However, under reducing conditions, the cobalt center is reduced to Co(II) or even Co(I), which are usually denoted as B 12r and B 12s , for reduced and super reduced respectively
Whilst most people obtain adequate B12 through a balanced diet containing animal products, certain groupsincluding vegans, older adults, and those with malabsorption conditionsmay need additional attention to their B12 status
Histology and histopathology, 17(3), 707714
While high-dose oral B12 (1,000 mcg daily) may be effective in some cases, intramuscular hydroxocobalamin remains the standard NHS practice
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