The accelerated healing in burns of treated mice includes the activity of the pentadecapeptide BPC 157 (Figure 1), given locally (as a cream) or systemically (ip), on the inflammatory cells, edema, reticulin, collagen, necrosis, blood vessel formation, number of preserved follicles, re-epithelization, tensile breaking strength, and water content in burned skin
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These effects (i.e., rapidly reestablished reorganized blood flow) attenuated/eliminated the lesions in the brain (intracerebral and intraventricular hemorrhage), heart (congestion, myocardial infarction, severe arrhythmias), lung (hemorrhage), and congestion in the liver, kidney, and gastrointestinal tract [52,53]
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O2 + e O2 Fe2+ + H2O2 Fe3+ + OH + OH 2 H2O2 2 H2O + O2 GSH + ROOH GSSG + ROH + H2O Correct Answer: Fe2+ + H2O2 Fe3+ + OH + OH Q12
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