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Yoo HC, et al

GHRH injections in elderly men improved some measures of muscle strength (upright row, shoulder press) but did not consistently improve physical function or IGF-I levels

But its more than just your metabolism (metabolic rate) slowing several factors lead to weight gain during hypothyroidism

doi: 10.1016/j.redox.2019.101116 9

Researchers now see promise in using glutathione, which they say has been shown to protect the brain in animal studies by counteracting these toxic radicals and preventing the forming of oxidative stress