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In the present investigation, mice treated with GLP showed a significant decrease in WBC counts

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In summary, the pathomechanisms of acute COVID-19 infection in the CV system include direct viral toxicity, intracellular viral entry via ACE2 and glycocalyx modulation, alteration of ACE2 signaling cascade towards the activation of harmful Ang II/AT1R axis, activation of pro-inflammatory proteins and deregulation of the immune system, hyper-inflammatory milieu and cytokine storm formation, hyper-coagulopathy development, ED and damage (Figure 2), and cardiac fibrosis and cardiac remodeling (23, 114)