We know that quality matters
Nurx established its reputation in womens health, particularly birth control, STI testing, and sexual health, before expanding into weight management
Despite the substantial conformational dynamics when bound to AMY 3 R, Cagri maintains the bypass conformation across the motions, likely arising from the consistent TMD and linker interactions between RAMP3 and CTR that enable robust engagement of residues within the Cagri bypass motif
My concern is that these meds don't fix the habits, emotional dysregulation, & lack of movement/exercise that often lead to obesity Neither do they fix the fact our current food system in much of the world is full of frankenfoods which are designed to promote overeating, or structural issues around the pressures on people which mean they don't have time or money to eat healthier more expensive less processed food, or move more I'm also concerned that - even for people that the above isn't a concern - that there isn't the appropriate support given as standard around nutritional education, lifestyle modification, resistance training, & emotional/mindset repatterning which are vital for ensuring that what people are eating is optimal for long term health and that they're taking the necessary actions to preserve muscle Thank you for this scientifically rigorous but also humane breakdown Lucy Jones - it is extremely important to have dietetic & nutritional perspective on this highly emotive issue
No published case reports document permanent allodynia from semaglutide or tirzepatide use
Asian J Neurosurg (2016) 11:317
